Immune Support

Daily Immune-Enhancing Formula

with Echinacea, Garlic, Goldenseal
and Medicinal Mushrooms

Keep your immune system healthy on a daily basis with this superior formula of immune-enhancing herbs. Our new formula contains high potencies of Astragalus, Ligustrum, and Echinacea in addition to a full spectrum of medicinal mushrooms and support nutrients.

Suggested dose: 1 capsule, 2 times per day for general immune enhancement. May be increased to 2 caps, 3 times per day for acute infections or additional immune support.

Each (two) capsules contain:
Echinacea angustifolia root (4% echinacoside) 100 mg
Astragalus membranaceus root extract 250 mg
Maitake mushroom TD-fraction extract 25 mg
Maitake mushroom powder 100 mg
Shiitake mushroom powder 200 mg
Reishi mushroom powder 100 mg
Ligustrum lucidum fruit extract 100 mg
Goldenseal root (Hydrastis canadensis) 10 mg
Quercetin 50 mg
Garlic (Allium sativum) bulb powder 50 mg
Vitamin A (as beta carotene) 2,500 IU
Vitamin C (as ascorbic acid) 100 mg
Vitamin B-6 5 mg
Folic acid 400 mcg
Vitamin B-12 5 mcg
Pantothenic acid 5 mg
Zinc 10 mg

REFERENCES

1.) Clement-Kruzel S, Hwang SA, Kruzel MC, Dasgupta A, Actor JK. Immune modulation of macrophage pro-inflammatory response by goldenseal and Astragalus extracts. J Med Food. 2008 Sep;11(3):493-8.
2.) Schoop R, Klein P, Suter A, Johnston SL.Echinacea in the prevention of induced rhinovirus colds: a meta-analysis. Clin Ther. 2006 Feb;28(2):174-83.
3.) Giles JT, Palat CT 3rd, Chien SH, Chang ZG, Kennedy DT. Evaluation of echinacea for treatment of the common cold. Pharmacotherapy. 2000 Jun;20(6):690-7.
4.) Abdullah T.A strategic call to utilize Echinacea-garlic in flu-cold seasons.J Natl Med Assoc. 2000 Jan;92(1):48-51.
5.) See DM, Broumand N, Sahl L, Tilles JG. In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients. Immunpharmacol 1997;35:229–35.
6.) Leuttig B, Steinmuller C, Gifford GE, et al. Macrophage activation by the polysaccharide arabinogalactan isolated from plant cell cultures of Echinacea purpurea. J Natl Cancer Inst 1989;81:669–75.
7.) Melchart D, Linde K, Worku F, et al. Immunomodulation with Echinacea—a systematic review of controlled clinical trials. Phytomedicine 1994;1:245–54.
8.) Dorn M, Knick E, Lewith G. Placebo-controlled, double-blind study of Echinacea pallida redix in upper respiratory tract infections. Comp Ther Med 1997;5:40–2.
9.) Hoheisel O, Sandberg M, Bertram S, et al. Echinacea shortens the course of the common cold: a double-blind, placebo-controlled clinical trial. Eur J Clin Res 1997;9:261–8.
10.) Braunig B, Dorn M, Knick E. Echinacea purpurea root for strengthening the immune response to flu-like infections. Zeitschrift Phytotherapie 1992;13:7–13.
11.) Brikenborn RM, Shah DV, Degenring FH. Echinaforce® and other Echinacea fresh plant preparations in the treatment of the common cold. A randomized, placebo-controlled, double-blind clinical trial. Phytomedicine 1999;6:1–5.
12.) Cho WC, Leung KN. In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cancer Lett. 2007 Jul 8;252(1):43-54. Epub 2007 Jan 16.
13.) Cho WC, Leung KN. In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus. J Ethnopharmacol. 2007 Aug 15;113(1):132-41. Epub 2007 May 31.
14.) Wang MS, Li J, Di HX, Li ZL, Yang SL, Hou W, Yan JY, Zhao XM. Clinical study on effect of Astragalus Injection and its immuno-regulation action in treating chronic aplastic anemia.Chin J Integr Med. 2007 Jun;13(2):98-102.
15.) Xu HD, You CG, Zhang RL, Gao P, Wang ZR.Xu HD, You CG, Zhang RL, Gao P, Wang ZR. J Int Med Res. 2007 Jan-Feb;35(1):84-90.
16.) Klepser T, Nisly N. Astragalus as an adjunctive therapy in immunocompromised patients. Alt Med Alert 1999;Nov:125–8 [review].
17.) Qun L, Luo Q, Zhang ZY, et al. Effects of astragalus on IL-2/IL-2R system in patients with maintained hemodialysis. Clin Nephrol 1999;52:333–4 [letter].
18.) Tang W, Eisenbrand G. Chinese Drugs of Plant Origin. Berlin: Springer Verlag, 1992, 1056.
19.) Nanba H, Hamaguchi AM, Kuroda H. The chemical structure of an antitumor polysaccharide in fruit bodies of Grifola frondosa (maitake). Chem Pharm Bull 1987;35:1162–8.
20.) Yamada Y, Nanba H, Kuroda H. Antitumor effect of orally administered extracts from fruit body of Grifola frondosa (maitake). Chemotherapy 1990;38:790–6.
21.) Nanba H. Immunostimulant activity in vivo and anti-HIV activity in vitro of 3 branched b-1–6-glucans extracted from maitake mushrooms (Grifola frondosa). VIII International Conference on AIDS, Amsterdam, 1992 [abstract].
22.) Shams-Ghahfarokhi M, Shokoohamiri MR, Amirrajab N, Moghadasi B, Ghajari A, Zeini F, Sadeghi G, Razzaghi-Abyaneh M. In vitro antifungal activities of Allium cepa, Allium sativum and ketoconazole against some pathogenic yeasts and dermatophytes. Fitoterapia. 2006 Jun;77(4):321-3. Epub 2006 May 11.
23.) Tessema B, Mulu A, Kassu A, Yismaw G. An in vitro assessment of the antibacterial effect of garlic (Allium sativum) on bacterial isolates from wound infections. Ethiop Med J. 2006 Oct;44(4):385-9.
24.) Pyun MS, Shin S.Antifungal effects of the volatile oils from Allium plants against Trichophyton species and synergism of the oils with ketoconazole. Phytomedicine. 2006 Jun;13(6):394-400. Epub 2005 Nov 2.
25.) Bakri IM, Douglas CW.Inhibitory effect of garlic extract on oral bacteria. Arch Oral Biol. 2005 Jul;50(7):645-51. Epub 2005 Feb 5.
26.) Bjarnsholt T, Jensen PØ, Rasmussen TB, Christophersen L, Calum H, Hentzer M, Hougen HP, Rygaard J, Moser C, Eberl L, Høiby N, Givskov M.Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections. Microbiology. 2005 Dec;151(Pt 12):3873-80.
27.) Dikasso D, Lemma H, Urga K, Debella A, Addis G, Tadele A, Yirsaw K. Investigation on the antibacterial properties of garlic (Allium sativum) on pneumonia causing bacteria. Ethiop Med J. 2002 Jul;40(3):241-9.
28.) Josling P. Preventing the common cold with a garlic supplement: a double-blind, placebo-controlled survey.Adv Ther. 2001 Jul-Aug;18(4):189-93.
29.) Kumar M, Berwal JS. Sensitivity of food pathogens to garlic (Allium sativum). J Appl Microbiol. 1998 Feb;84(2):213-5.
30.) Gomaa NF, Hashish MH.The inhibitory effect of garlic (Allium sativum) on growth of some microorganisms. J Egypt Public Health Assoc. 2003;78(5-6):361-72.
31.) Dankert J, Tromp TF, de Vries H, Klasen HJ. Antimicrobial activity of crude juices of Allium ascalonicum, Allium cepa and Allium sativum. Zentralbl Bakteriol [Orig A]. 1979 Oct;245(1-2):229-39.
32.) Wintergerst ES, Maggini S, Hornig DH. Contribution of selected vitamins and trace elements to immune function. Ann Nutr Metab.2007;51(4):301-23. Epub 2007 Aug 28.
33.) Wintergerst ES, Maggini S, Hornig DH. Contribution of selected vitamins and trace elements to immune function. Ann Nutr Metab. 2007;51(4):301-23. Epub 2007 Aug 28.
34.) Romieu I. Nutrition and lung health. Int J Tuberc Lung Dis. 2005 Apr;9(4):362-74.
35.) Mora JR, Iwata M, von Andrian UH. Vitamin effects on the immune system: vitamins A and D take centre stage. Nat Rev Immunol. 2008 Aug 8. [Epub ahead of print]
36.) Molina EL, Patel JA. A to Z: vitamin A and zinc, the miracle duo.Indian J Pediatr. 1996 Jul-Aug;63(4):427-31.
37.) Sasazuki S, Sasaki S, Tsubono Y, Okubo S, Hayashi M, Tsugane S.Effect of vitamin C on common cold: randomized controlled trial.Eur J Clin Nutr. 2006 Jan;60(1):9-17.
38.) Van Straten M, Josling P. Preventing the common cold with a vitamin C supplement: a double-blind, placebo-controlled survey. Adv Ther. 2002 May-Jun;19(3):151-9.
39.) Carr AB, Einstein R, Lai LY, Martin NG, Starmer GA. Vitamin C and the common cold: using identical twins as controls. Med J Aust. 1981 Oct 17;2(8):411-2.
40.) Anderson TW, Beaton GH, Corey P, Spero L. Winter illness and vitamin C: the effect of relatively low doses. Can Med Assoc J. 1975 Apr 5;112(7):823-6.
41.) Romieu I. Nutrition and lung health. Int J Tuberc Lung Dis. 2005 Apr;9(4):362-74.
42.) Wintergerst ES, Maggini S, Hornig DH. Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Ann Nutr Metab. 2006;50(2):85-94. Epub 2005 Dec 21.
43.) High KP. Nutritional strategies to boost immunity and prevent infection in elderly individuals. Clin Infect Dis. 2001 Dec 1;33(11):1892-900. Epub 2001 Oct 25.
44.) Girodon F, Galan P, Monget AL, Boutron-Ruault MC, Brunet-Lecomte P, Preziosi P, Arnaud J, Manuguerra JC, Herchberg S. Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients: a randomized controlled trial. MIN. VIT. AOX. geriatric network. Arch Intern Med. 1999 Apr 12;159(7):748-54.
45.) Romieu I. Nutrition and lung health. Int J Tuberc Lung Dis. 2005 Apr;9(4):362-74.